實驗室簡介

美國Oklahoma?Medical?Research?Foundation于蓬春博士實驗室正在招聘博士后研究人員。于博士一直致力于研究細胞代謝在血管發(fā)育、再生以及在相關(guān)血管疾病中的作用，其研究成果已經(jīng)以第一作者身份發(fā)表在Nature,?Circulation?Research等著名期刊。實驗室綜合使用小鼠遺傳學(xué)、細胞生物學(xué)、生物化學(xué)、代謝組學(xué)以及轉(zhuǎn)錄組學(xué)的相關(guān)技術(shù)來回答領(lǐng)域內(nèi)一系列的前沿問題，能夠為加入的博士后提供充足的研究資源和一流的科研訓(xùn)練。

Oklahoma?Medical?Research?Foundation，簡稱OMRF，成立于1946年，是一所獨立的、非營利性的高水平生物醫(yī)學(xué)研究機構(gòu)。研究所主要致力于心血管疾病、癌癥、以及自身免疫性疾病等重大疾病的基礎(chǔ)和轉(zhuǎn)化醫(yī)學(xué)研究。OMRF擁有超過700項美國和國際專利，并以部分專利技術(shù)為基礎(chǔ)成立了14個生物技術(shù)公司。OMRF研究實力強勁，擁有完善的科研平臺和支撐體系，包括Clinical?Genomics?Center、Human?Phenotyping?Core、Gnotobiotic?Mouse?Core、Quantitative?Analysis?Core等，能夠為前沿科學(xué)研究的開展提供充分的技術(shù)支持和保障。OMRF位于Oklahoma?City，毗鄰University?of?Oklahoma?Health?Sciences?Center和多個研究所，如Harold?Hamm?Diabetes?Center，Dean?McGee?Eye?Institute等，從而形成了一個研究氣氛濃郁、合作交流密切的學(xué)術(shù)共同體。Oklahoma?City是State?of?Oklahoma的首府，是一個非常宜居的城市。在那里可以體會到州府城市的大都會生活，如精致的飲食、NBA著名球隊雷霆隊的精彩比賽等。

OMRF非常重視對于博士后的培養(yǎng)。除了一流的研究條件和完善的福利待遇，研究所還通過諸如為博士后提供Travel?Awards等多項舉措促進博士后的職業(yè)發(fā)展。因此，OMRF連續(xù)多年進入《The?Scientist》雜志評選出的“Best?Places?to?Work?for?Postdocs”名單。

實驗室歡迎對血管和代謝生物學(xué)有興趣的青年研究人員的加入。請將申請發(fā)送至Pengchun-Yu@omrf.org。申請材料包括：

  1. Cover?letter:?請描述教育和研究經(jīng)歷、取得的研究成果和未來的研究興趣；
  2. Curriculum?vitae；
  3. 三位推薦人的姓名和聯(lián)系方式。

Postdoctoral Positions in Vascular Metabolism

美國于蓬春博士實驗室招聘博士后-肽度TIMEDOO

The laboratory of Dr. Pengchun Yu in the Cardiovascular Biology Research Program at the Oklahoma Medical Research Foundation (OMRF) is seeking postdoctoral scientists to investigate the metabolic regulation of vascular formation and its implications in vascular diseases.

The laboratory focuses on the interface between cellular metabolism and vascular biology. Dr. Yu has recently demonstrated that MYC/hexokinase 2 pathway-driven glucose metabolism in endothelial cells controls blood and lymphatic vessel formation dependent on fibroblast growth factor receptor (FGFR) signaling (Yu et al., Nature, 2017). Research projects of the laboratory will be built upon this important finding to further study the crosstalk between metabolic programs and angiogenic signaling events and to understand the involvement of cellular metabolism in the pathogenesis of vascular diseases. Multidisciplinary strategies will be employed, ranging from novel genetically-modified mouse models to cutting-edge systems biology tools including metabolomics and single-cell transcriptome analysis.

OMRF is an independent, nonprofit biomedical research institute. The innovative basic and translational research at OMRF covers several critical areas such as cardiovascular disease, autoimmune disease, and cancer. OMRF has made The Scientist magazine’s annual list of the “Best Places to Work for Postdocs” for many years. The institute offers postdoctoral fellows an exceptional research and training environment with state-of-the-art facilities and outstanding core technology laboratories including imaging, next-generation sequencing, and clinical genomics. Moreover, postdoctoral scientists are encouraged to apply for OMRF Postdoc Travel Awards to support their attendance at meetings or workshops.

Applicants should have a recent Ph.D. (or expect to receive a doctoral degree soon), possess excellent experimental and communication skills, and demonstrate solid training in cell biology, biochemistry, developmental biology, or mouse genetics with scientific publications. Previous research experience in metabolism is a plus but is not required. In addition to competitive salaries and comprehensive benefits, the successful candidates will be provided with strong support for developing an independent research career after postdoctoral training.

Please send (1) a cover letter describing your previous training, research accomplishments, and future research interests, (2) your curriculum vitae, and (3) contact information of three references to Dr. Pengchun Yu at Pengchun-Yu@omrf.org.